Utilizing the Skin Microbiome For UV Protection- Can a Startup Do It?
Despite recent developments in modern therapeutics for skin cancer, it is still the most common cancer in the world, with over 13 million cases diagnosed annually only in the USA, which causing to approximately 65,200 direct deaths. About 90 percent of non-melanoma skin cancers and about 86 percent of melanomas are associated with exposure to ultra violet (UV) radiation from the sun, and also 90 percent of skin maturing signs are correlated to UV exposure. The skin cancer prevention guidelines includes, avoiding sun exposure, covering up, and wearing broad spectrum sunscreens. Sunscreens are important part of photo-protection, and although advances in technology have occurred, sunscreens still provide limited protection stems from several of reasons as: lack of deep UVA protection, poor photo-stability, challenging formulation capabilities, and negative tactile effects. There is an urgent need for broad spectrum, including UVA protection, stable, and more potent formulations for UV protection. TopgeniX bring new approach to the commercial UV filter industry, based on skin-microbiome and evolutionary conservative compounds, considered as nature’s sunscreen, known as Mycosporine-like Amino-Acids (MAAs). TopgeniX strives to develop a revolutionary natural-based UV filters to attain broad spectrum, stable, non-irritating, and efficient UV protection.